8:45 am
Registration & Morning Coffee

9:15 am Chair’s Opening Remarks

Developing Scalable Analytical Frameworks to Validate Bioprocessing & Characterize the End Product

9:30 am Evaluating the Efficiency of Each Step of Downstream Processing to Validate Decision Making

  • Brandon Hsu Senior Manager - Process Development, Shiru


  • Implementing in-process analytics to monitor efficiency
  • Interpreting outputs to effectively deduce process efficiency and technique efficacy
  • Understanding how to engineer processes in the context of the outputs

10:00 am Developing Assays to Characterize the Product in the Context of Commercialization


  • Implementing scalable analytical frameworks to validate the product’s profile
  • Identifying which impurities have been produced in the process, and whether this is consistent between batches
  • Overcoming the cost burden of chromatography with novel techniques

10:30 am
Morning Networking Break & Scientific Poster Session


Learn from your peers about their latest scientific insights and gain up-to-date data from companies sharing their exciting work.

Contribute towards the conversation and share your cutting-edge research to you fellow downstream process development community to:

  • Communicate your breakthrough discoveries to a vast audience of experts
  • Learn how others are tackling similar challenges to you

Optimizing Purification to Achieve Sufficient Product Quality & Quantity at Scale

11:30 am Designing Processes That Balance Product Purity, Quality, & Yield to Ensure a Scalable and Commercially Viable DSP

  • Patrick Stoddard Research & Development DSP, Protein Biochemist Lead Scientist, New Culture


  • Establishing quantitative specifications for organoleptic properties of food proteins to guide process design and optimization
  • Comparing different methods to improve product quality while maintaining yield and purity
  • Effectively adapting existing processes for scaling partners 

12:00 pm Concentrating the Supernatant with Cost-Effective Techniques That Maintain Product Integrity


  • Validating the filtration membranes are correct for the purpose of the protein
  • Cooling down the system to prevent denaturation of the protein
  • Recovering the protein after the precipitation step to ensure to protein remains active and functiona

12:30 pm Roundable Discussion: Counteracting the Risk of Denaturing Thermosensitive Proteins & Damaging Cells During Downstream Processing with Equipment Selection to Maintain Functionality


  • Ensuring that equipment selection guarantees the integrity of proteins and cells
  • Understanding the factors that need to be mitigated against
  • Discussing the cost burden of improper equipment selection 

1:15 pm
Networking Lunch

Managing Relationships with Contract Manufacturing Facilities & Taking Ownership of Pilot Plants to Accelerate Product Development

2:15 pm CMO Matchmaking: Accelerated Path to “I Do”


  • Assessing the technical and physical capacity of contract facilities
  • Troubleshooting technical downstream processing challenges at a distance to prevent the outsourcing bottleneck
  • Aligning manufacturers’ capabilities with commercial objectives

2:45 pm DSP Facilities & Engineering Considerations & Challenges from a Cultivated Meat Perspective


  • The scale-up and right sizing requirement – how to ensure facilities are fit for purpose for the downstream and commercial scale perspective
  • The constant balance between CAPEX, facility maintenance, quality and technical teams to ensure product quality and commercial viability
  • SciFi Foods’ experience in DSP and lessons learned to date

3:15 pm Chair’s Closing Remarks

3:30 pm End of Conference